Jonas Neher
Group Leader
Jonas has been leading
the lab since 2015. He is excited by new discoveries
and by applying new technologies to understand the mechanisms of neurodegenerative disease.
Jessica Wagner
Senior Scientist
Jessy is our expert for
medin amyloid and a crucial team-member. She has
developed many methods
for the detection and analysis of medin amyloidosis
in the aging and Alzheimer's
disease brain.
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Natasa Schwarz
PhD Student
Natasa is investigating medin amyloid and its role in vascular aging, focusing on identifying the proteases involved in its formation. She is also characterising a novel medin mutation and developing new mouse models to study its pathological impact.
Desirée Brösamle
Postdoc
Desirée is our bioinformatics and molecular biology specialist. She studies microglial heterogeneity in aging and Alzheimer's disease using single cell profiling approaches.
Nina Hermann
PhD Student
Nina is developing our research on metabolic microglial reprogramming in Alzheimer disease and studies behavioural changes after microglial manipulation.
Marleen Veit
PhD Student
Marleen is investigating medin amyloid and its role in age-related vascular dysfunction and Alzheimer disease and is characterising new mouse models of medin pathology.
Xidi Yuan
Postdoc
Xidi is our neuroimmunology expert, exploring how inflammation contributes to vascular amyloidosis. She uses immune profiling approaches to examine cellular and molecular changes, helping to uncover how immune responses affect vascular pathology.
Thomas Lewis
Postdoc
Tom is investigating how amyloidosis pathology affects brain blood flow using his expertise in longitudinal in vivo imaging. He has developed and optimized advanced imaging approaches to monitor cerebrovascular function, providing critical insights into how amyloidosis alters vascular dynamics and contributes to disease progression.
Yuanyuan Deng
Postdoc
Yuanyuan is studying how aging impacts blood vessels and the brain. With a PhD in Biomedical Science (2022) and a background in Pharmacology and Neuroscience, she spends her days working with mice and human tissues, chasing elusive proteins, and keeping a sense of humor in science. Outside the lab, she runs marathons and builds Lego cities with her daughter.
Atilay Ilgün
PhD Student
Atilay holds a master’s degree in Bioinformatics and Systems Biology, with a focus on single-cell multi-omic analyses in Alzheimer’s disease. His current research centers on single-cell multiome approaches to explore transcriptomic and epigenetic dynamics of microglia in Alzheimer’s pathology.
Ramona Rodde
Technical Assistant
Ramona supports the team with genotyping, biochemical analysis, tissue sectioning/staining and other lab stuff.
Tsuneko Mishima
Postdoc
Tsuneko specializes in in vivo imaging of glial dynamics under physiological conditions. Building on her experience with 2-photon and fiber photometry approaches, she is now advancing ultrasound and photoacoustic imaging methods to investigate age-related vascular amyloidosis across large regions of the brain.
Anna Schmidtner
Postdoc
Anna combines sequencing and computational biology approaches to uncover patterns of cellular behaviour. Her work integrates pathway analysis, gene expression profiling, and topic modelling to identify how distinct cell populations respond under different physiological and pathological conditions.
Krisztina Zeller
Technical Assistant
Kris supports the lab’s experimental and operational work through her expertise in genotyping, tissue processing, immunohistochemistry, and biochemical assays. She also plays a key role in maintaining the smooth day-to-day running of the lab and ensuring the quality and consistency of experimental workflows.
Gezhi Yan
PhD student
Gezhi’s work focuses on vascular health in the aging brain and Alzheimer’s disease using vascular imaging methods, and studies the interplay between vascular dysfunction, amyloid pathology, and inflammation.
Christian Schrader
PhD student
Paula Jobst
Intern
Who We Are
Alumni
Dr. Karoline Degenhardt
Dr. Ann-Christin Wendeln
Dr. Ping Liu
Katleen Wild
Lisa Steinbrecher